reviewInternational Journal of NanomedicineDec 1, 2020GOLD OA

<p>A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle</p>

National University of Sciences and Technology · University of Houston

PubMed
Indexed incrossrefdoajpubmed

Abstract

Metal nanoparticles are being extensively used in biomedical fields due to their small size-to-volume ratio and extensive thermal stability. Gold nanoparticles (AuNPs) are an obvious choice for biomedical applications due to their amenability of synthesis, stabilization, and functionalization, low toxicity, and ease of detection. In the past few decades, various chemical methods have been used for the synthesis of AuNPs, but recently, newer environment friendly green approaches for the synthesis of AuNPs have gained attention. AuNPs can be conjugated with a number of functionalizing moieties including ligands, therapeutic agents, DNA, amino acids, proteins, peptides, and oligonucleotides. Recently, studies…

Citation impact

505
total citations
FWCI
15.13
Percentile
100%
References
341
Citations per year

Authors

2

Topics & keywords

Keywords
  • Colloidal gold
  • Surface modification
  • Drug delivery
  • Nanotechnology
  • Nanoparticle
  • Materials science
  • Nanomedicine
  • Conjugated system
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