Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Massachusetts General Hospital · Center for Neuro-Oncology · +7 more institutions
Abstract
Substantial progress has been made over the past two decades in detecting, predicting and promoting recovery of consciousness in patients with disorders of consciousness (DoC) caused by severe brain injuries. Advanced neuroimaging and electrophysiological techniques have revealed new insights into the biological mechanisms underlying recovery of consciousness and have enabled the identification of preserved brain networks in patients who seem unresponsive, thus raising hope for more accurate diagnosis and prognosis. Emerging evidence suggests that covert consciousness, or cognitive motor dissociation (CMD), is present in up to 15–20% of patients with DoC and that detection of CMD in the intensive care unit can…
Citation impact
- FWCI
- 39.92
- Percentile
- 100%
- References
- 300
Authors
4- BLBrian L. EdlowCorresponding
Massachusetts General Hospital, Center for Neuro-Oncology, Athinoula A. Martinos Center for Biomedical Imaging
- JCJan Claassen
NewYork–Presbyterian Hospital, Columbia University Irving Medical Center, New York Hospital Queens
- NDNicholas D. Schiff
Cornell University, MIND Research Institute
- DMDavid M. Greer
Boston University
Topics & keywords
- Persistent vegetative state
- Consciousness
- Consciousness Disorders
- Neuroimaging
- Minimally conscious state
- Neuroscience
- Medicine
- Psychology
- Good health and well-being