Chemically Modified Biopolymers for the Formation of Biomedical Hydrogels

Biopolymers are natural polymers sourced from plants and animals, which include a variety of polysaccharides and polypeptides. The inclusion of biopolymers into biomedical hydrogels is of great interest because of their inherent biochemical and biophysical properties, such as cellular adhesion, degradation, and viscoelasticity. The objective of this Review is to provide a detailed overview of the design and development of biopolymer hydrogels for biomedical applications, with an emphasis on biopolymer chemical modifications and cross-linking methods. First, the fundamentals of biopolymers and chemical conjugation methods to introduce cross-linking groups are described. Cross-linking methods to form biopolymer…

• NI
  National Institute of Allergy and Infectious Diseases

  Awards: R01AR056624, R01AR077362
• DO
  Division of Materials Research

  Award: DMR-1720530
• DO
  Division of Civil, Mechanical and Manufacturing Innovation

  Award: CMMI: 15-48571