Large-scale neural recordings call for new insights to link brain and behavior

Neuroscientists today can measure activity from more neurons than ever before, and are facing the challenge of connecting these brain-wide neural recordings to computation and behavior. In the present review, we first describe emerging tools and technologies being used to probe large-scale brain activity and new approaches to characterize behavior in the context of such measurements. We next highlight insights obtained from large-scale neural recordings in diverse model systems, and argue that some of these pose a challenge to traditional theoretical frameworks. Finally, we elaborate on existing modeling frameworks to interpret these data, and argue that the interpretation of brain-wide neural recordings calls…

• SF
  Simons Foundation

  Award: 543003
• IB
  International Brain Research Organization
• DA
  Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften
• NI
  National Institutes of Health

  Awards: 1U19NS107613, 1U19NS107613-01, R01EB026953, DP2NS116768
• NI
  National Institute of Neurological Disorders and Stroke

  Award: 1U19NS107613-01