reviewPLoS neglected tropical diseasesDec 4, 2025GOLD OA

Laboratory diagnosis of melioidosis

Mahidol University · Royal Brisbane and Women's Hospital · +15 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an infectious disease with high rates of morbidity and mortality, which primarily affects low- and middle-income countries in South and Southeast Asia and Australia. The clinical manifestations of this disease are nonspecific and, therefore, rapid laboratory diagnosis is especially critical as appropriate management requires specific antimicrobials. This article aims to provide an overview of the current diagnostic methodologies, emerging technologies, susceptibility testing, and future perspectives for laboratory diagnosis of melioidosis. By examining conventional culture methods, mass spectrometry, antimicrobial susceptibility…

Citation impact

67
total citations
FWCI
2.14
Percentile
99%
References
124
Citations per year

Authors

13

Topics & keywords

Keywords
  • Melioidosis
  • Burkholderia pseudomallei
  • Isolation (microbiology)
  • Microbiology
  • MacConkey agar
  • Agar
  • Biology
  • Antimicrobial
UN Sustainable Development Goals
  • Life in Land
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Funding