Multiple sclerosis and related disorders

Abstract This chapter describes the clinical features and modern treatment of multiple sclerosis and related immune-mediated inflammatory disorders of the central nervous system (CNS), including neuromyelitis optica spectrum disorders (NMOSD), MOG antibody disease (MOGAD) and acute disseminated encephalomyelitis (ADEM) as well as site-restricted inflammatory disorders which may occur in isolation, optic neuritis, and transverse myelitis.