Experimental and Therapeutic Medicine
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Abstract
Abstract. Cancer cachexia occurs in the majority of cancer patients before death, and it is responsible for the death of 22% of cancer patients. One of the most relevant characteristics of cachexia is that of asthenia, which reflects significant muscle wasting noted in cachectic cancer patients The aim of the present study was to assess whether the β2-adrenergic agonist formoterol is associated with an improvement in physiological parameters such as grip force and total physical activity in cachetic rats. Administration of the β2-agonist formoterol (0.3 mg/kg for 7 days) in rats bearing Yoshida AH-130 ascites hepatoma tumors, a model which induces a strong loss of both body and muscle weight, resulted in a…
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Topics & keywords
Topics
Keywords
- Cachexia
- Wasting
- Molecular medicine
- Cancer
- Medicine
- Agonist
- Formoterol
- Internal medicine
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