New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
Jinan University · First Affiliated Hospital of Zhengzhou University · +3 more institutions
Abstract
With the development of proteomics and epigenetics, a large number of RNA-binding proteins (RBPs) have been discovered in recent years, and the interaction between long non-coding RNAs (lncRNAs) and RBPs has also received increasing attention. It is extremely important to conduct in-depth research on the lncRNA-RBP interaction network, especially in the context of its role in the occurrence and development of cancer. Increasing evidence has demonstrated that lncRNA-RBP interactions play a vital role in cancer progression; therefore, targeting these interactions could provide new insights for cancer drug discovery. In this review, we discussed how lncRNAs can interact with RBPs to regulate their localization,…
Citation impact
- FWCI
- 26.48
- Percentile
- 100%
- References
- 166
Authors
7- ZYZi‐Ting Yao
Jinan University
- YYYuan‐Han Yang
Jinan University
- MSMiaomiao Sun
First Affiliated Hospital of Zhengzhou University
- YHYan He
Xinjiang Medical University, Jinan University, Fifth Affiliated Hospital of Xinjiang Medical University, Guangzhou Medical University
- LLLong Liao
Xinjiang Medical University, Jinan University, Fifth Affiliated Hospital of Xinjiang Medical University, Guangzhou Medical University
Topics & keywords
- RNA-binding protein
- Biology
- Computational biology
- Epigenetics
- Interaction network
- Context (archaeology)
- RNA
- Protein–protein interaction
- Good health and well-being