reviewNeuroImageJan 1, 2022GOLD OA

Quantitative mapping of the brain’s structural connectivity using diffusion MRI tractography: A review

Harvard University · Brigham and Women's Hospital · +9 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo reconstruction of the brain's white matter connections at macro scale. It provides an important tool for quantitative mapping of the brain's structural connectivity using measures of connectivity or tissue microstructure. Over the last two decades, the study of brain connectivity using dMRI tractography has played a prominent role in the neuroimaging research landscape. In this paper, we provide a high-level overview of how tractography is used to enable quantitative analysis of the brain's structural connectivity in health and disease. We focus on two types of quantitative analyses of tractography,…

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