Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors

Sedentary behaviors, particularly prolonged sitting and lack of physical activity, may influence survival after cancer.

To examine the independent and joint associations of daily sitting time and leisure-time physical activity with mortality outcomes among cancer survivors. DESIGN, SETTING, AND PARTICIPANTS: A prospective cohort of a nationally representative sample of cancer survivors, age 40 years or older (n = 1535; weighted population, 14 002 666), from the US National Health and Nutrition Examination Survey from 2007 to 2014. Participants were linked to mortality data from their interview and physical examination date through December 31, 2015. Daily sitting time and leisure-time physical activity (LTPA) were self-reported using the Global Physical Activity Questionnaire. Data analyses were performed from January 1 to May 1, 2021. MAIN OUTCOMES AND MEASURES: All-cause, cancer-specific, and noncancer mortality.