Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method
Atatürk University · King Saud University
Abstract
Heavy metals are essential for a wide range of biological processes, including the growth and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the body’s immunity, but their excessive intake is harmful. Specifically, they cause oxidative stress (OS) and generate free radicals and reactive oxygen species (ROS) in metabolism. In addition, the accumulation of heavy metals in humans can cause serious damage to different organs, especially respiratory, nervous and reproductive and digestive systems. Biologically, metal chelation therapy is often used to treat metal toxicity. This process occurs through the interaction between the ligand and a central metal atom, forming a complex…
Citation impact
- FWCI
- 54.34
- Percentile
- 100%
- References
- 157
Authors
2Topics & keywords
- Chelation
- Biomolecule
- Antioxidant
- Chemistry
- Metal
- Metal poisoning
- Reactive oxygen species
- Metal ions in aqueous solution