The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review

University of Glasgow · Clínica Diagonal · +3 more institutions

PubMed
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Abstract

The physiological effects of physical exercise are ubiquitously reported as beneficial to the cardiovascular and musculoskeletal systems. Exercise is widely promoted by medical professionals to aid both physical and emotional wellbeing; however, mechanisms through which this is achieved are less well understood. Despite numerous beneficial attributes, certain types of exercise can inflict significant significant physiological stress. Several studies document a key relationship between exercise and immune activation. Activation of the innate immune system occurs in response to exercise and it is proposed this is largely mediated by cytokine signalling. Cytokines are typically classified according to their…

Citation impact

279
total citations
FWCI
25.15
Percentile
100%
References
122
Citations per year

Authors

8

Topics & keywords

Keywords
  • Immune system
  • Inflammation
  • Cytokine
  • Physical exercise
  • Narrative review
  • Medicine
  • Physical activity
  • Immunology
UN Sustainable Development Goals
  • Good health and well-being
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