Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection
Institute of Cellular and Organismic Biology, Academia Sinica · Institute of Biomedical Sciences, Academia Sinica · +2 more institutions
Abstract
The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public health crisis that demands the timely creation of new therapeutics and viral detection. Owing to their high specificity and reliability, monoclonal antibodies (mAbs) have emerged as powerful tools to treat and detect numerous diseases. Hence, many researchers have begun to urgently develop Ab-based kits for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ab drugs for use as COVID-19 therapeutic agents. The detailed structure of the SARS-CoV-2 spike protein is known, and since this protein is key for viral infection, its receptor-binding domain (RBD) has become a major target for therapeutic Ab…
Citation impact
- FWCI
- 24.70
- Percentile
- 100%
- References
- 294
Authors
9- YHYu‐Chyi HwangCorresponding
Institute of Cellular and Organismic Biology, Academia Sinica
- RLRuei‐Min Lu
Institute of Biomedical Sciences, Academia Sinica, Biomedical Translation Research Center
- SSShih-Chieh Su
Institute of Cellular and Organismic Biology, Academia Sinica
- PCPao-Yin Chiang
Institute of Biomedical Sciences, Academia Sinica, Biomedical Translation Research Center
- SKShih-Han Ko
Institute of Biomedical Sciences, Academia Sinica, Biomedical Translation Research Center
Topics & keywords
- Coronavirus disease 2019 (COVID-19)
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Virology
- 2019-20 coronavirus outbreak
- Monoclonal antibody
- Betacoronavirus
- Medicine
- Antibody
- Good health and well-being