Impact of antibiotics on the human microbiome and consequences for host health
Teagasc - The Irish Agriculture and Food Development Authority · University College Cork · +1 more institution
Abstract
It is well established that the gut microbiota plays an important role in host health and is perturbed by several factors including antibiotics. Antibiotic-induced changes in microbial composition can have a negative impact on host health including reduced microbial diversity, changes in functional attributes of the microbiota, formation, and selection of antibiotic-resistant strains making hosts more susceptible to infection with pathogens such as Clostridioides difficile. Antibiotic resistance is a global crisis and the increased use of antibiotics over time warrants investigation into its effects on microbiota and health. In this review, we discuss the adverse effects of antibiotics on the gut microbiota…
Citation impact
- FWCI
- 55.27
- Percentile
- 100%
- References
- 283
Authors
5- DPDhrati Patangia
Teagasc - The Irish Agriculture and Food Development Authority, University College Cork, APC Microbiome Institute
- CACornelius Anthony Ryan
University College Cork
- EDEugene Dempsey
University College Cork
- RPReynolds Paul Ross
University College Cork, APC Microbiome Institute
- CSCatherine StantonCorresponding
Teagasc - The Irish Agriculture and Food Development Authority, APC Microbiome Institute
Topics & keywords
- Antibiotics
- Microbiome
- Antibiotic resistance
- Host (biology)
- Biology
- Gut flora
- Human health
- Microbiology