Curcumin: Biological Activities and Modern Pharmaceutical Forms
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Abstract
Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a natural lipophilic polyphenol that exhibits significant pharmacological effects in vitro and in vivo through various mechanisms of action. Numerous studies have identified and characterised the pharmacokinetic, pharmacodynamic, and clinical properties of curcumin. Curcumin has an anti-inflammatory, antioxidative, antinociceptive, antiparasitic, antimalarial effect, and it is used as a wound-healing agent. However, poor curcumin absorption in the small intestine, fast metabolism, and fast systemic elimination cause poor bioavailability of curcumin in human beings. In order to overcome these problems, a number of curcumin formulations…
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317
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6Topics & keywords
Topics
Keywords
- Curcumin
- Bioavailability
- Chemistry
- Polyphenol
- Chromatography
- Extraction (chemistry)
- High-performance liquid chromatography
- Sample preparation
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