reviewGutFeb 1, 2022HYBRID OA

Gut microbiome and health: mechanistic insights

University of Helsinki · Wageningen University & Research · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The gut microbiota is now considered as one of the key elements contributing to the regulation of host health. Virtually all our body sites are colonised by microbes suggesting different types of crosstalk with our organs. Because of the development of molecular tools and techniques (ie, metagenomic, metabolomic, lipidomic, metatranscriptomic), the complex interactions occurring between the host and the different microorganisms are progressively being deciphered. Nowadays, gut microbiota deviations are linked with many diseases including obesity, type 2 diabetes, hepatic steatosis, intestinal bowel diseases (IBDs) and several types of cancer. Thus, suggesting that various pathways involved in immunity, energy,…

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2,245
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Authors

4

Topics & keywords

Keywords
  • Microbiome
  • Computational biology
  • Gut microbiome
  • Biology
  • Bioinformatics
  • Data science
  • Medicine
  • Computer science
UN Sustainable Development Goals
  • Good health and well-being
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