Homologous and Heterologous Covid-19 Booster Vaccinations
University of Maryland, Baltimore · Baylor College of Medicine · +19 more institutions
Abstract
Although the three vaccines against coronavirus disease 2019 (Covid-19) that have received emergency use authorization in the United States are highly effective, breakthrough infections are occurring. Data are needed on the serial use of homologous boosters (same as the primary vaccine) and heterologous boosters (different from the primary vaccine) in fully vaccinated recipients.
virus particles, or BNT162b2 (Pfizer-BioNTech) at a dose of 30 μg. The primary end points were safety, reactogenicity, and humoral immunogenicity on trial days 15 and 29.
Citation impact
- FWCI
- 60.19
- Percentile
- 100%
- References
- 32
Authors
38- RLRobert L. AtmarCorresponding
University of Maryland, Baltimore, Baylor College of Medicine, The University of Texas Medical Branch at Galveston
- KEKirsten E. Lyke
University of Maryland, Baltimore, The University of Texas Medical Branch at Galveston
- MEMeagan E. Deming
University of Maryland, Baltimore, The University of Texas Medical Branch at Galveston
- LALisa A. Jackson
University of Maryland, Baltimore, Kaiser Permanente Washington Health Research Institute, University of Washington, The University of Texas Medical Branch at Galveston
- ARAngela R Branche
University of Maryland, Baltimore, University of Rochester, The University of Texas Medical Branch at Galveston
Topics & keywords
- Medicine
- Reactogenicity
- Booster dose
- Immunogenicity
- Vaccination
- Regimen
- Neutralizing antibody
- Immunology
- Good health and well-being
Funding
- PPfizer
- MModerna
- NINational Institutes of HealthAwards: 75N93019C00050, UM1AI48372, UM1AI148373, UM1AI148573, UM1AI148574, UM1AI148450, UM1AI148452, UM1AI148575, UM1AI148576, UM1AI148684
- NINational Institute of Allergy and Infectious DiseasesAwards: UM1AI148573, UM1AI148684, UM1AI148450, UM1AI148689, UM1AI148575, UM1AI148372, 75N93019C00050, UM1AI148574, UM1AI148452, UM1AI148576, UM1AI148373