Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
National Cancer Research Institute · Chiba Cancer Center · +3 more institutions
Indexed incrossrefpubmed
Abstract
No abstract available for this paper.
Citation impact
814
total citations
- FWCI
- 61.41
- Percentile
- 100%
- References
- 86
Citations per year
Authors
46Topics & keywords
Topics
Keywords
- Effector
- Tumor microenvironment
- Glycolysis
- Blockade
- Cancer research
- CD8
- Downregulation and upregulation
- PD-L1
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.
Funding
- BSBristol-Myers Squibb
- ELEli Lilly and Company
- PPfizer
- AAstraZeneca
- NNovartis
- RRoche
- AAbbVie
- MSMeso Scale Diagnostics
- SMSuzuken Memorial Foundation
- TSTakeda Science Foundation
- TPTakeda Pharmaceutical Company
- JRJapan Research Foundation for Clinical Pharmacology
- NCNational Cancer CenterAwards: 31-A-7, 28-A-7
- JAJapan Agency for Medical Research and Development
- TPTaiho Pharmaceutical
- NCNational Cancer Center Japan
- GJGlaxoSmithKline Japan
- SFSGH Foundation
- JCJapan Cancer Society
- MOMinistry of Education, Culture, Sports, Science and TechnologyAwards: 19ae0101074s0401, 16cm0106301h000 1, 19cm0106335h0002
- DDaiichi-Sankyo
- DSDainippon Sumitomo Pharma
- EEisai
- IKIchiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care
- KLKowa Life Science Foundation
- KHKyowa Hakko Kirin
- APAstellas Pharma
- DSDaiwa Securities Health Foundation
- YMYasuda Memorial Medical Foundation
- PTPrincess Takamatsu Cancer Research Fund
- HGHitachi Global Foundation
- OPOno Pharmaceutical
- MLMSD Life Science Foundation, Public Interest Incorporated Foundation
- CPChugai Pharmaceutical
- JSJapan Society for the Promotion of ScienceAwards: 16H06279, 202101784