Glioma targeted therapy: insight into future of molecular approaches

Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically, gliomas occur among all ages, more often seen in adults, which males are more susceptible than females. According to the fifth edition of the WHO Classification of Tumors of the Central Nervous System (WHO CNS5), standard of care and prognosis of gliomas can be dramatically different. Generally, circumscribed gliomas are usually benign and recommended to early complete resection, with chemotherapy if necessary. Diffuse gliomas and other high-grade gliomas according to their molecule subtype are slightly intractable, with necessity of chemotherapy. However, for glioblastoma, feasible resection followed by radiotherapy…

• NN
  National Natural Science Foundation of China

  Awards: 2018M633002, 2018JJ3838, 2018SK2101, 82073893, 81703622, 82172685, NO.82073893, 81873635, C2019186
• CS
  Central South University
• CP
  China Postdoctoral Science Foundation

  Awards: 81873635, 82073893, 81703622, C2019186, 2018JJ3838, 2018SK2101, 2018M633002
• NS
  Natural Science Foundation of Hunan Province

  Awards: 81703622, C2019186, 2018M633002, 81873635, 2018SK2101, 2018JJ3838, 82073893
• PR
  Postdoctoral Research Foundation of China

  Award: 2018M633002
• XH
  Xiangya Hospital, Central South University

  Award: 2018JJ3838