American Journal of Perinatology Reports

Anti-M red blood cell (RBC) alloantibodies are observed in 0.3% of pregnant women, 1 in which it causes hemolytic disease of the fetus/newborn; currently, no standard treatment method has been established.It is managed by plasmapheresis and high-dose intravenous immunoglobulin (IVIG) therapy that are conventionally used for treating Rh blood-type alloimmunization during pregnancy.We report a unique case of a pregnant woman who had intrauterine fetal death (IUFD) in two previous pregnancies; the detected titers of anti-M antibodies were very low.Informed consent was obtained from the mother for publication of this case report. Case ReportA 25-year-old woman presented to us at 8 weeks of pregnancy with a history…