articleACS Applied Materials & InterfacesFeb 23, 2022Closed access

Dendritic Hydrogels with Robust Inherent Antibacterial Properties for Promoting Bacteria-Infected Wound Healing

Wenzhou Medical University · Nanjing University of Science and Technology · +1 more institution

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Abstract

Bacterial infections are a common problem associated with wound treatment that imposes a significant burden on healthcare systems and patients. As a result, healthcare providers urgently need new treatment strategies to protect people. Hydrogel biomaterials with inherent antimicrobial properties offer an attractive and viable solution to this issue. Here, for the first time, we have developed a new efficient synthetic strategy to prepare cationic hydrogels (PHCI) with intrinsically efficient antimicrobial properties by chemically cross-linking trans-1,4-cyclohexanediamine with 1,3-dibromo-2-propanol using a condensation reaction without the use of toxic cross-linking agents. As expected, the prepared PHCI…

Citation impact

341
total citations
FWCI
31.80
Percentile
100%
References
41
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Authors

9

Topics & keywords

Keywords
  • Self-healing hydrogels
  • Materials science
  • Wound healing
  • Self-healing
  • Antibacterial activity
  • Nanotechnology
  • Bacteria
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
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