reviewMaterials Today BioFeb 21, 2022GOLD OA

Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

Army Medical University · Xinqiao Hospital · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and rheumatoid arthritis (RA). Currently, available treatment options for inflammatory arthritis include anti-inflammatory medications administered via oral, topical, or intra-articular routes, surgery, and physical rehabilitation. Novel alternative approaches to managing inflammatory arthritis, so far, remain the grand challenge owing to catastrophic financial burden and insignificant therapeutic benefit. In the view of non-targeted systemic cytotoxicity and limited bioavailability of drug therapies, a major concern is…

Citation impact

373
total citations
FWCI
57.05
Percentile
100%
References
167
Citations per year

Authors

6

Topics & keywords

Keywords
  • Medicine
  • Synovitis
  • Rheumatoid arthritis
  • Arthritis
  • Osteoarthritis
  • Drug delivery
  • Inflammatory arthritis
  • Inflammation
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding