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reviewOxidative Medicine and Cellular LongevityJan 1, 2022HYBRID OA

[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

Universidad del Azuay · Arturo Prat University · +10 more institutions

Indexed incrossrefdoaj

Abstract

Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in pomegranate ( Punica granatum L.) and in wood and bark of some tree species. Structurally, EA is a dilactone of hexahydroxydiphenic acid (HHDP), a dimeric gallic acid derivative, produced mainly by hydrolysis of ellagitannins, a widely distributed group of secondary metabolites. EA is attracting attention due to its antioxidant, anti‐inflammatory, antimutagenic, and antiproliferative properties. EA displayed pharmacological effects in various in vitro and in vivo model systems. Furthermore, EA has also been well documented for its antiallergic,…

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