reviewSignal Transduction and Targeted TherapyFeb 14, 2022GOLD OA

Therapeutic peptides: current applications and future directions

Zhejiang Sci-Tech University · Nanjing University of Chinese Medicine · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and delivery strategies, which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field. A wide variety of natural and modified peptides have been obtained and studied, covering multiple therapeutic areas. This review summarizes the efforts and achievements in peptide drug discovery, production, and modification, and their current applications. We also discuss the value and challenges associated with future…

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1,927
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FWCI
147.87
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100%
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557
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Authors

9

Topics & keywords

Keywords
  • Drug discovery
  • Biochemical engineering
  • Drug delivery
  • Nanotechnology
  • Computer science
  • Computational biology
  • Data science
  • Engineering
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