reviewMolecular CancerFeb 18, 2022GOLD OA

Exosomes as a new frontier of cancer liquid biopsy

Jiangsu University · Nantong Tumor Hospital · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction. Exosomes are a subset of extracellular vesicles (EVs) that shuttle molecular cargoes from donor cells to recipient cells and play a crucial role in mediating intercellular communication. Increasing studies suggest that exosomes have a great promise to serve as novel biomarkers in liquid biopsy, since large quantities of exosomes are enriched in body fluids and are involved in numerous physiological and pathological processes. However, the further clinical application of exosomes has been greatly restrained by the…

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832
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Authors

8

Topics & keywords

Keywords
  • Microvesicles
  • Liquid biopsy
  • Frontier
  • Biology
  • Cancer
  • Cancer research
  • Biopsy
  • Pathology
UN Sustainable Development Goals
  • Good health and well-being
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