Exosomes as a new frontier of cancer liquid biopsy
Jiangsu University · Nantong Tumor Hospital · +3 more institutions
Abstract
Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction. Exosomes are a subset of extracellular vesicles (EVs) that shuttle molecular cargoes from donor cells to recipient cells and play a crucial role in mediating intercellular communication. Increasing studies suggest that exosomes have a great promise to serve as novel biomarkers in liquid biopsy, since large quantities of exosomes are enriched in body fluids and are involved in numerous physiological and pathological processes. However, the further clinical application of exosomes has been greatly restrained by the…
Citation impact
- FWCI
- 66.44
- Percentile
- 100%
- References
- 212
Authors
8Topics & keywords
- Microvesicles
- Liquid biopsy
- Frontier
- Biology
- Cancer
- Cancer research
- Biopsy
- Pathology
- Good health and well-being