A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

The emerging understanding of gut microbiota as 'metabolic machinery' influencing many aspects of physiology has gained substantial attention in the field of psychiatry. This is largely due to the many overlapping pathophysiological mechanisms associated with both the potential functionality of the gut microbiota and the biological mechanisms thought to be underpinning mental disorders. In this systematic review, we synthesised the current literature investigating differences in gut microbiota composition in people with the major psychiatric disorders, major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia (SZ), compared to 'healthy' controls. We also explored gut microbiota composition…

• P
  Pfizer
• PR
  PA Research Foundation
• CC
  Clifford Craig Foundation
• JB
  Jack Brockhoff Foundation
• AG
  Australian Government
• ES
  European Space Agency
• BU
  Bond University
• MS
  Multiple Sclerosis Australia
• AA
  Australian Academy of Science
• AR
  Australian Rotary Health
• BB
  Beyond Blue
• LT
  La Trobe University
• DU
  Deakin University
• RU
  RMIT University
• UO
  University of Melbourne

  Award: 1156072
• SW
  Swisse Wellness
• S
  Servier
• HL
  H. Lundbeck A/S
• ES
  Epilepsy Society
• NI
  National Institutes of Health
• A
  Allergan
• MR
  Medical Research Council
• NH
  National Health and Medical Research Council

  Award: 1156072
• CC
  Cancer Council Queensland