Mechanism-Based Design of Efficient PET Hydrolases
Universität Greifswald · Masaryk University · +4 more institutions
Abstract
Polyethylene terephthalate (PET) is the most widespread synthetic polyester, having been utilized in textile fibers and packaging materials for beverages and food, contributing considerably to the global solid waste stream and environmental plastic pollution. While enzymatic PET recycling and upcycling have recently emerged as viable disposal methods for a circular plastic economy, only a handful of benchmark enzymes have been thoroughly described and subjected to protein engineering for improved properties over the last 16 years. By analyzing the specific material properties of PET and the reaction mechanisms in the context of interfacial biocatalysis, this Perspective identifies several limitations in…
Citation impact
- FWCI
- 19.77
- Percentile
- 100%
- References
- 185
Authors
11Topics & keywords
- Mechanism (biology)
- Chemistry
- Catalysis
- Computer science
- Biochemical engineering
- Combinatorial chemistry
- Biochemistry
- Engineering
- Responsible consumption and production