Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration
Shanghai Jiao Tong University · Shanghai Ninth People's Hospital · +3 more institutions
Abstract
Bone defects combined with tumors, infections, or other bone diseases are challenging in clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but they can cause a series of complications. To address this problem, researchers have constructed various implantable biomaterials. However, the original pathological microenvironment of bone defects, such as residual tumors, severe infection, or other bone diseases, could further affect bone regeneration. Thus, the rational design of versatile biomaterials with integrated bone therapy and regeneration functions is in great demand. Many strategies have been applied to fabricate smart stimuli-responsive materials for bone therapy and…
Citation impact
- FWCI
- 30.89
- Percentile
- 100%
- References
- 163
Authors
5- HWHongpu Wei
Shanghai Jiao Tong University, Shanghai Ninth People's Hospital
- JCJinjie Cui
Shanghai Jiao Tong University, Shanghai Ninth People's Hospital
- KLKaili Lin
Shanghai Jiao Tong University, Shanghai Stomatological Hospital, Shanghai Ninth People's Hospital
- JXJing XieCorresponding
Sichuan University, State Key Laboratory of Oral Diseases
- XWXudong Wang
Shanghai Jiao Tong University, Shanghai Stomatological Hospital, Shanghai Ninth People's Hospital
Topics & keywords
- Regeneration (biology)
- Bone healing
- Bone tissue
- Tissue engineering
- Biomedical engineering
- Medicine
- Neuroscience
- Cell biology
Funding
- NNNational Natural Science Foundation of ChinaAwards: YG2021ZD12, SKLOD2021OF01, 82071096, 82072396, 81871490, 81771047, 19XD1434500, 21490711700, 20191819
- SAScience and Technology Commission of Shanghai MunicipalityAwards: 19XD1434500, 20XD1433100, 21490711700, 20191819
- SJShanghai Jiao Tong UniversityAwards: YG2021ZD12, 20191819
- SKState Key Laboratory of Oral DiseaseAwards: 81871490, 82072396, 20191819, SKLOD2021OF01, 19XD1434500
- POProgram of Shanghai Academic Research LeaderAwards: 20XD1433100, SKLOD2021OF01, 20191819, 81871490, 19XD1434500, 82072396