reviewInternational Journal of Oral ScienceMar 2, 2022GOLD OA

Oral microbiota in human systematic diseases

Sichuan University · State Key Laboratory of Oral Diseases · +3 more institutions

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Abstract

Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The dynamic oral microbiota cooperates with the host to reflect the information and status of immunity and metabolism through two-way communication along the oral cavity and the systemic organs. The oral cavity is one of the most important interaction windows between the human body and the environment. The microenvironment at different sites in the oral cavity has different microbial compositions and is regulated by complex signaling, hosts, and external environmental factors. These processes may affect or reflect human health because certain health states seem to be related to the composition of oral bacteria, and the…

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