reviewMolecular CancerMar 18, 2022GOLD OA

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

Central University of Kashmir · Qatar Airways (Qatar) · +15 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical oncology, offering ease in tumor sampling, continuous monitoring by repeated sampling, devising personalized therapeutic regimens, and screening for therapeutic resistance. Liquid biopsies consist of isolating tumor-derived entities like circulating tumor cells, circulating tumor DNA, tumor extracellular vesicles, etc., present in the body fluids of patients with cancer, followed by an analysis of genomic and proteomic data contained within them. Methods for isolation and analysis of liquid…

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791
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Authors

12

Topics & keywords

Keywords
  • Liquid biopsy
  • Precision medicine
  • Circulating tumor cell
  • Extracellular vesicles
  • Cancer
  • Personalized medicine
  • Biopsy
  • Precision oncology
UN Sustainable Development Goals
  • Good health and well-being
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