Antibody evasion properties of SARS-CoV-2 Omicron sublineages
Aaron Diamond AIDS Research Center · Columbia University · +2 more institutions
Abstract
Abstract The identification of the Omicron (B.1.1.529.1 or BA.1) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1 immediately caused concern owing to the number of alterations in the spike glycoprotein that could lead to antibody evasion. We 2 and others 3–6 recently reported results confirming such a concern. Continuing surveillance of the evolution of Omicron has since revealed the rise in prevalence of two sublineages, BA.1 with an R346K alteration (BA.1+R346K, also known as BA.1.1) and B.1.1.529.2 (BA.2), with the latter containing 8 unique spike alterations and lacking 13 spike alterations found in BA.1. Here we extended our studies to include…
Citation impact
- FWCI
- 85.28
- Percentile
- 100%
- References
- 27
Authors
19- SISho IketaniCorresponding
Aaron Diamond AIDS Research Center, Columbia University
- LLLihong Liu
Aaron Diamond AIDS Research Center, Columbia University
- YGYicheng Guo
Aaron Diamond AIDS Research Center, Columbia University
- LLLiyuan Liu
Aaron Diamond AIDS Research Center, Columbia University
- JFJasper Fuk‐Woo Chan
Hong Kong Science and Technology Parks Corporation, University of Hong Kong
Topics & keywords
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Virology
- Coronavirus disease 2019 (COVID-19)
- Antibody
- 2019-20 coronavirus outbreak
- Evasion (ethics)
- Biology
- Medicine
- Good health and well-being