articleAnalytical ChemistryMar 9, 2022Closed access

Liposome-Mediated In Situ Formation of Type-I Heterojunction for Amplified Photoelectrochemical Immunoassay

YGYuan GaoYZYongyi ZengXLXiaolong LiuDTDianping Tang

Fuzhou University · Fujian Medical University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Exploiting innovative sensing mechanisms and their rational implementation for selective and sensitive detection has recently become one of the mainstream research directions of photoelectrochemical (PEC) bioanalysis. In contrast to existing conventional strategies, this study presents a new liposome-mediated method via in situ combining ZnInS nanosheets (ZIS NSs) with SnS2 to form a ZIS NSs/SnS2 type-I heterojunction on fluorine-doped tin oxide (FTO) electrodes for highly sensitive PEC immunoassays. Specifically, alkaline phosphatase (ALP)-encapsulated liposomes were confined within 96-well plates by sandwich immunorecognition and subsequently subjected to lysis treatment. Enzymatically produced H2S by the…

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Topics & keywords

Topics
Keywords
  • Chemistry
  • Detection limit
  • Heterojunction
  • Tin oxide
  • Biosensor
  • Immunoassay
  • Bioanalysis
  • Electrode
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