Photobiocatalysis for Abiological Transformations

Harnessing biocatalysts for novel abiological transformations is a longstanding goal of synthetic chemistry. Combining the merits of biocatalysis and photocatalysis allows for selective transformations fueled by visible light and offers many advantages including new reactivity, high enantioselectivity, greener syntheses, and high yields. Photoinduced electron or energy transfer enables synthetic methodologies that complement conventional two electron processes or offer orthogonal pathways for developing new reactions. Enzymes are well suited and can be tuned by directed evolution to exert control over open-shell intermediates, thereby suppressing undesirable reactions and delivering high chemo- and…

• NS
  National Science Foundation

  Awards: CHE-1205189, 1205189
• UD
  U.S. Department of Energy

  Awards: CHE-1205189, DE-SC0018420, SC0018420
• DO
  Division of Chemistry

  Award: CHE-1205189
• BA
  Biological and Environmental Research

  Award: DE-SC0018420