reviewACS Applied Nano MaterialsMar 4, 2022HYBRID OA

Synergistic Effects Between Metal Nanoparticles and Commercial Antimicrobial Agents: A Review

AIAna Isabel RibeiroADAlice DiasAZAndréa Zille

University of Minho

PubMed
Indexed incrossrefpubmed

Abstract

Nanotechnology has expanded into a broad range of clinical applications. In particular, metal nanoparticles (MNPs) display unique antimicrobial properties, a fundamental function of novel medical devices. The combination of MNPs with commercial antimicrobial drugs (e.g., antibiotics, antifungals, and antivirals) may offer several opportunities to overcome some disadvantages of their individual use and enhance effectiveness. MNP conjugates display multiple advantages. As drug delivery systems, the conjugates can extend the circulation of the drugs in the body, facilitate intercellular targeting, improve drug stabilization, and possess superior delivery. Concomitantly, they reduce the required drug dose,…

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258
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17.33
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100%
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226
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Authors

3

Topics & keywords

Topics
Keywords
  • Antimicrobial
  • Drug delivery
  • Drug
  • Nanotechnology
  • Antibiotics
  • Broad spectrum
  • Antimicrobial drug
  • Pharmacology
UN Sustainable Development Goals
  • Good health and well-being
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