reviewSignal Transduction and Targeted TherapyApr 23, 2022GOLD OA

Microbiota in health and diseases

Shantou University · First Affiliated Hospital of Shantou University Medical College · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

The role of microbiota in health and diseases is being highlighted by numerous studies since its discovery. Depending on the localized regions, microbiota can be classified into gut, oral, respiratory, and skin microbiota. The microbial communities are in symbiosis with the host, contributing to homeostasis and regulating immune function. However, microbiota dysbiosis can lead to dysregulation of bodily functions and diseases including cardiovascular diseases (CVDs), cancers, respiratory diseases, etc. In this review, we discuss the current knowledge of how microbiota links to host health or pathogenesis. We first summarize the research of microbiota in healthy conditions, including the gut-brain axis,…

Citation impact

2,902
total citations
FWCI
219.07
Percentile
100%
References
419
Citations per year

Authors

11

Topics & keywords

Keywords
  • Dysbiosis
  • Gut flora
  • Immune system
  • Immunology
  • Pathogenesis
  • Disease
  • Biology
  • Fecal bacteriotherapy
UN Sustainable Development Goals
  • Good health and well-being
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