articleNature CommunicationsApr 25, 2022GOLD OA

Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

JCJianzhong ChenATAngela TamVKValeria KebetsCOCsaba OrbánLQLeon Qi Rong Ooi

National University of Singapore · Yale-NUS College · +10 more institutions

PubMed
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Abstract

How individual differences in brain network organization track behavioral variability is a fundamental question in systems neuroscience. Recent work suggests that resting-state and task-state functional connectivity can predict specific traits at the individual level. However, most studies focus on single behavioral traits, thus not capturing broader relationships across behaviors. In a large sample of 1858 typically developing children from the Adolescent Brain Cognitive Development (ABCD) study, we show that predictive network features are distinct across the domains of cognitive performance, personality scores and mental health assessments. On the other hand, traits within each behavioral domain are…

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Topics
Keywords
  • Connectome
  • Resting state fMRI
  • Cognition
  • Psychology
  • Human Connectome Project
  • Personality
  • Cognitive psychology
  • Big Five personality traits
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