Brain charts for the human lifespan

Abstract Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual differences in neuroimaging metrics over time, in contrast to growth charts for anthropometric traits such as height and weight 1 . Here we assemble an interactive open resource to benchmark brain morphology derived from any current or future sample of MRI data ( http://www.brainchart.io/ ). With the goal of basing these reference charts on the largest and most inclusive dataset available, acknowledging limitations due to known biases of MRI studies relative to the diversity of the global population, we…

• UR
  UK Research and Innovation
• MR
  Medical Research Council

  Awards: MC_PC_17209, MC_G0802534, MR/S020306/1, MC_UU_00002/2, MR/K020706/1, MC_UU_00030/2, MC_PC_17228, MR/J009482/1, MC_PC_17230, MC_UU_00002/2, MC_UU_00030/8, MR/N022556/1, MR/K006355/1, MR/N026063/1, MR/M009041/1
• BA
  Biotechnology and Biological Sciences Research Council

  Award: BB/H008217/1
• NI
  National Institute of Mental Health

  Awards: K08MH120564, T32MH019112