articleFrontiers in NutritionApr 4, 2022GOLD OA

Radical Scavenging Mechanisms of Phenolic Compounds: A Quantitative Structure-Property Relationship (QSPR) Study

MPMelanie PlatzerSKSandra KieseTTThorsten TybussekTHThomas HerfellnerFSFranziska Schneider

Fraunhofer Institute for Process Engineering and Packaging · Technical University of Munich · +2 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Due to their antioxidant properties, secondary plant metabolites can scavenge free radicals such as reactive oxygen species and protect foods from oxidation processes. Our aim was to study structural influences, like basic structure, number of hydroxyl groups and number of Bors criteria on the outcome of the oxygen radical absorbance capacity (ORAC) assay. Furthermore, similarities and differences to other in vitro antioxidant assays were analyzed by principal component analysis. Our studies confirmed that the antioxidant behavior in the ORAC assay is dominated by the number and types of substituents and not by the Bors criteria, as long as no steric hindrance occurs. For example, morin (MOR) with five…

Citation impact

265
total citations
FWCI
23.14
Percentile
100%
References
82
Citations per year

Authors

7

Topics & keywords

Topics
Keywords
  • Chemistry
  • Radical
  • ABTS
  • Oxygen radical absorbance capacity
  • DPPH
  • Antioxidant
  • Quantitative structure–activity relationship
  • Polyphenol
No related works found for this paper.

Funding