Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies
University of Würzburg · Universitätsklinikum Würzburg · +4 more institutions
Abstract
Most patients survive acute myocardial infarction (MI). Yet this encouraging development has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend to have more comorbidities worsening economic strain on healthcare systems and impeding effective medical management. The heart's pathological changes in structure and/or function, termed myocardial remodelling, significantly impact on patient outcomes. Risk factors like diabetes, chronic obstructive pulmonary disease, female sex, and others distinctly shape disease progression on the 'road to HF'. Despite the availability of HF drugs that interact with general pathways involved in myocardial remodelling, targeted drugs remain…
Citation impact
- FWCI
- 76.12
- Percentile
- 100%
- References
- 159
Authors
5- SFStefan FrantzCorresponding
University of Würzburg, Universitätsklinikum Würzburg
- MHMoritz Hundertmark
John Radcliffe Hospital, University of Oxford
- JSJeanette Schulz‐Menger
Charité - Universitätsmedizin Berlin
- FMFrank M. Bengel
Medizinische Hochschule Hannover
- JBJohann Bauersachs
Medizinische Hochschule Hannover
Topics & keywords
- Medicine
- Myocardial infarction
- Heart failure
- Cardiology
- Pathophysiology
- Internal medicine
- Intensive care medicine
- Risk stratification
- No poverty