articleScientific ReportsJan 11, 2022GOLD OA

PET microplastics affect human gut microbiota communities during simulated gastrointestinal digestion, first evidence of plausible polymer biodegradation during human digestion

ATAlba TamargoNMNatalia MolineroJJJulián J. ReinosaVAVictor Alcolea-RodriguezRPRaquel Portela

Instituto de Investigación en Ciencias de la Alimentación · Universidad Autónoma de Madrid · +3 more institutions

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Abstract

Microplastics (MPs) are a widely recognized global problem due to their prevalence in natural environments and the food chain. However, the impact of microplastics on human microbiota and their possible biotransformation in the gastrointestinal tract have not been well reported. To evaluate the potential risks of microplastics at the digestive level, completely passing a single dose of polyethylene terephthalate (PET) through the gastrointestinal tract was simulated by combining a harmonized static model and the dynamic gastrointestinal simgi model, which recreates the different regions of the digestive tract in physiological conditions. PET MPs started several biotransformations in the gastrointestinal tract…

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277
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13.11
Percentile
100%
References
74
Citations per year

Authors

8
  • AT
    Alba TamargoCorresponding

    Instituto de Investigación en Ciencias de la Alimentación, Universidad Autónoma de Madrid

  • NM
    Natalia Molinero

    Instituto de Investigación en Ciencias de la Alimentación, Universidad Autónoma de Madrid

  • JJ
    Julián J. Reinosa

    Ayuntamiento de Castellón de la Plana, Instituto de Cerámica y Vidrio

  • VA
    Victor Alcolea-Rodriguez

    Instituto de Catálisis y Petroleoquímica

  • RP
    Raquel Portela

    Instituto de Catálisis y Petroleoquímica

Topics & keywords

Keywords
  • Microplastics
  • Gastrointestinal tract
  • Human gastrointestinal tract
  • Microbiome
  • Digestion (alchemy)
  • Microorganism
  • Digestive tract
  • Human health
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