reviewSeminars in Cell and Developmental BiologyApr 4, 2022HYBRID OA

Human placental development and function

TCTereza Cindrová‐DaviesANAmanda N. Sferruzzi‐Perri

University of Cambridge

PubMed
Indexed incrossrefpubmed

Abstract

The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it facilitates delivery of oxygen and nutrients and removal of waste products. Not surprisingly, defective early placental development is the primary cause of common disorders of pregnancy, including recurrent miscarriage, fetal growth restriction, pre-eclampsia and stillbirth. Adverse pregnancy conditions will also affect the life-long health of the fetus via developmental programming[1]. Despite its critical importance in reproductive success and life-long health, our understanding of placental development is not…

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244
total citations
FWCI
37.39
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100%
References
195
Citations per year

Authors

2

Topics & keywords

Topics
Keywords
  • Placenta
  • Fetus
  • Pregnancy
  • Miscarriage
  • Trophoblast
  • Intrauterine growth restriction
  • Placentation
  • Placental insufficiency
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