Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations
Soochow University · Chinese Academy of Medical Sciences & Peking Union Medical College · +1 more institution
Abstract
The triglyceride-glucose (TyG) index has been identified as a reliable alternative biomarker of insulin resistance (IR). Recently, a considerable number of studies have provided robust statistical evidence suggesting that the TyG index is associated with the development and prognosis of cardiovascular disease (CVD). Nevertheless, the application of the TyG index as a marker of CVD has not systemically been evaluated, and even less information exists regarding the underlying mechanisms associated with CVD. To this end, in this review, we summarize the history of the use of the TyG index as a surrogate marker for IR. We aimed to highlight the application value of the TyG index for a variety of CVD types and to…
Citation impact
- FWCI
- 131.57
- Percentile
- 100%
- References
- 101
Authors
5Topics & keywords
- Medicine
- Biomarker
- Insulin resistance
- Index (typography)
- Triglyceride
- Surrogate endpoint
- Angiology
- Diabetes mellitus