reviewVirusesMay 5, 2022GOLD OA

A Review on Chikungunya Virus Epidemiology, Pathogenesis and Current Vaccine Development

TYThaíse Yasmine Vasconcelos de Lima CavalcantiMRMylena Ribeiro PereiraSOSérgio Oliveira de PaulaRFRafael Freitas de Oliveira França

Fundação Oswaldo Cruz · Universidade Federal Rural de Pernambuco · +1 more institution

PubMed
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Abstract

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile illness known as chikungunya fever (CHIKF). Infection is self-limited and characterized mainly by severe joint pain and myalgia that can last for weeks or months; however, severe disease presentation can also occur in a minor proportion of infections. Among the atypical CHIKV manifestations that have been described, severe arthralgia and neurological complications, such as encephalitis, meningitis, and Guillain-Barré Syndrome, are now reported in many outbreaks. Moreover, death cases were also reported, placing CHIKV as a relevant…

Citation impact

236
total citations
FWCI
41.41
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100%
References
131
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Authors

4

Topics & keywords

Topics
Keywords
  • Chikungunya
  • myalgia
  • Medicine
  • Disease
  • Outbreak
  • Virology
  • Immunology
  • Virus
UN Sustainable Development Goals
  • Good health and well-being
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