articleScienceMay 5, 2022Closed access

Highly efficient catalytic production of oximes from ketones using in situ–generated H 2 O 2

Cardiff University · Ube (Japan) · +6 more institutions

PubMed
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Abstract

The ammoximation of cyclohexanone using preformed hydrogen peroxide (H 2 O 2 ) is currently applied commercially to produce cyclohexanone oxime, an important feedstock in nylon-6 production. We demonstrate that by using supported gold-palladium (AuPd) alloyed nanoparticles in conjunction with a titanium silicate-1 (TS-1) catalyst, H 2 O 2 can be generated in situ as needed, producing cyclohexanone oxime with >95% selectivity, comparable to the current industrial route. The ammoximation of several additional simple ketones is also demonstrated. Our approach eliminates the need to transport and store highly concentrated, stabilized H 2 O 2 , potentially achieving substantial environmental and economic…

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254
total citations
FWCI
16.28
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100%
References
70
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Authors

14

Topics & keywords

Keywords
  • Cyclohexanone
  • Cyclohexanone oxime
  • Catalysis
  • Hydrogen peroxide
  • Oxime
  • Raw material
  • Palladium
  • Selectivity
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