articleNew England Journal of MedicineNov 16, 2016BRONZE OA

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

Western University · Robarts Clinical Trials · +18 more institutions

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Abstract

Ustekinumab, a monoclonal antibody to the p40 subunit of interleukin-12 and interleukin-23, was evaluated as an intravenous induction therapy in two populations with moderately to severely active Crohn's disease. Ustekinumab was also evaluated as subcutaneous maintenance therapy.

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Authors

27

Topics & keywords

Keywords
  • Ustekinumab
  • Medicine
  • Crohn's disease
  • Maintenance therapy
  • Interleukin 23
  • Monoclonal antibody
  • Monoclonal
  • Disease
UN Sustainable Development Goals
  • Good health and well-being
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