Eight‐year weight losses with an intensive lifestyle intervention: The look AHEAD study
TLThe Look AHEAD Research Group
Indexed incrossrefpubmed
Abstract
Objective
To evaluate 8-year weight losses achieved with intensive lifestyle intervention (ILI) in the Look AHEAD (Action for Health in Diabetes) study. DESIGN AND METHODS: Look AHEAD assessed the effects of intentional weight loss on cardiovascular morbidity and mortality in 5,145 overweight/obese adults with type 2 diabetes, randomly assigned to ILI or usual care (i.e., diabetes support and education [DSE]). The ILI provided comprehensive behavioral weight loss counseling over 8 years; DSE participants received periodic group education only.
Results
All participants had the opportunity to complete 8 years of intervention before Look AHEAD was halted in September 2012; ≥88% of both groups completed the 8-year outcomes assessment. ILI and DSE participants lost (mean ± SE) 4.7% ± 0.2% and 2.1 ± 0.2% of initial weight, respectively (P
Citation impact
815
total citations
- FWCI
- 38.86
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- 100%
- References
- 42
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Authors
1- TLThe Look AHEAD Research GroupCorresponding
University of Pennsylvania
Topics & keywords
Topics
Keywords
- Medicine
- Weight loss
- Overweight
- Obesity
- Type 2 diabetes
- Diabetes mellitus
- Intervention (counseling)
- Gerontology
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.
Funding
- UDU.S. Department of Health and Human Services
- UDU.S. Department of Veterans AffairsAward: M01RR01346
- LLifeScanAwards: DK56990, DK57182, DK57154, DK57178, DK57177, DK 046204, DK57151, M01RR01066, DK57171, DK57078, DK57008, DK56992, M01RR000056, DK57002, DK57219, DK57149, M01RR00051, M01RR01346, M01RR0021140, UL1 RR 024153, M01RR02719, DK57131, P30 DK48520, DK57135, DK57136
- NYNew York City Department of Health and Mental Hygiene
- MGMassachusetts General HospitalAwards: DK57151, DK57219, DK57182, UL1 RR 024153, M01RR01066, DK57008, DK57178, DK57154, M01RR00051, DK57136, P30 DK48520, DK57171, DK57177, DK57149, DK57002, M01RR000056, DK56992, DK 046204, M01RR02719, M01RR01346, DK56990, DK57131, M01RR0021140, DK57078, DK57135
- MIMassachusetts Institute of TechnologyAwards: DK 046204, P30 DK48520, DK57182, DK57154, DK57002, DK57149, DK57178, M01RR01346, DK57135, DK57171, DK57151, DK57078, M01RR02719, UL1 RR 024153, DK57008, M01RR01066, M01RR000056, DK56990, DK57177, DK56992, M01RR0021140, DK57219, DK57136, DK57131, M01RR00051
- JHJohns Hopkins UniversityAward: M01RR02719
- UOUniversity of PittsburghAwards: DK57131, DK57008, DK57154, M01RR01346, M01RR01066, DK57078, DK56990, DK57178, DK57002, DK57177, DK56992, P30 DK48520, DK 046204, M01RR02719, DK57151, M01RR0021140, DK57149, M01RR000056, UL1 RR 024153, M01RR00051, DK57136, DK57171, DK57219, DK57182, DK57135
- DKDeutsches KrebsforschungszentrumAward: M01RR000056
- NINational Institutes of HealthAwards: DK56992, DK48520, DK57136, P30 DK48520, DK57219, M01RR01066, DK57078, M01RR0021140, M01RR00051, DK57136, DK57149, DK56990, DK57177, DK57171, DK57151, DK57182, DK57131, DK57002, DK57078, DK57154, M01RR000056, DK57002, DK 046204, M01RR02719, DK57171, DK57151, DK57008, 046204, DK57177, DK57178, DK56990, DK57154, DK57131, DK57182, DK57135, M01RR01346, UL1 RR 024153, DK57149
- CFCenters for Disease Control and PreventionAwards: M01RR02719, M01RR000056, DK57135, DK57154, DK57131, M01RR00051, DK 046204, DK57008, M01RR01346, DK56992, M01RR0021140, DK57177, DK57151, P30 DK48520, M01RR01066, UL1 RR 024153, DK57182, DK57171, DK56990, DK57136, DK57149, DK57078, DK57219, DK57002, DK57178
- NHNational Heart, Lung, and Blood InstituteAwards: DK57219, M01RR02719, DK57131, DK57154, DK57151, DK56992, DK57078, M01RR000056, DK57177, M01RR01346, M01RR0021140, DK 046204, DK57182, DK57002, DK57149, M01RR01066, UL1 RR 024153, DK57008, DK57135, P30 DK48520, DK57136, DK57178, DK56990, DK57171, M01RR00051
- NINational Institute of Nursing ResearchAwards: M01RR01346, DK57219, DK57008, M01RR0021140, DK57002, DK57177, M01RR000056, M01RR01066, DK57171, DK57182, DK57135, DK57131, DK 046204, DK57151, P30 DK48520, UL1 RR 024153, M01RR00051, DK57136, DK56990, DK57178, DK57078, DK56992, DK57149, M01RR02719
- NINational Institute of Diabetes and Digestive and Kidney DiseasesAwards: M01RR0021140, DK48520, P30 DK48520, DK57149, DK57182, M01RR000056, M01RR01066, DK57008, DK57219, DK 046204, DK57078, M01RR02719, M01RR01346, DK57131, UL1 RR 024153, DK56992, M01RR00051, DK57136
- NCNational Center on Minority Health and Health DisparitiesAwards: DK57136, M01RR01066, M01RR00051, DK57171, M01RR02719, M01RR000056, DK57182, DK57154, DK57177, DK 046204, DK57135, M01RR0021140, UL1 RR 024153, DK57008, DK57178, DK57002, DK57151, P30 DK48520, DK56990, DK57078, DK56992, DK57149, M01RR01346, DK57219, DK57131
- OOOffice of Research on Women's HealthAwards: M01RR02719, DK57008, DK57135, DK56990, DK57002, P30 DK48520, DK57177, DK56992, DK57182, DK57151, DK57149, DK57219, DK57078, M01RR000056, M01RR01346, DK57171, UL1 RR 024153, DK57178, M01RR01066, M01RR00051, DK57154, DK57136, DK57131, DK 046204, M01RR0021140
- NINational Institute on Minority Health and Health Disparities