reviewEuropean Journal of NeurologySep 5, 2017HYBRID OA

Alzheimer's disease

CLChris LaneJHJohn HardyJMJonathan M. Schott

UK Dementia Research Institute · University College London

PubMed
Indexed incrossrefdoajpubmed

Abstract

Alzheimer's disease, the commonest cause of dementia, is a growing global health concern with huge implications for individuals and society. In this review, current understanding of the epidemiology, genetics, pathology and pathogenesis of Alzheimer's disease is outlined, before its clinical presentation and current treatment strategies are discussed. Finally, the review discusses how our enhanced understanding of Alzheimer pathogenesis, including the recognition of a protracted preclinical phase, is informing new therapeutic strategies with the aim of moving from treatment to prevention.

Citation impact

2,518
total citations
FWCI
74.45
Percentile
100%
References
77
Citations per year

Authors

3

Topics & keywords

Topics
Keywords
  • Medicine
  • Disease
  • Dementia
  • Epidemiology
  • Presentation (obstetrics)
  • Pathogenesis
  • Alzheimer's disease
  • Neuroscience
No related works found for this paper.

Funding