reviewJournal of Clinical OncologyJul 31, 2017Closed access

Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update

Duke Medical Center

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Abstract

Purpose To update the ASCO guideline for antiemetics in oncology. Methods ASCO convened an Expert Panel and conducted a systematic review of the medical literature for the period of November 2009 to June 2016. Results Forty-one publications were included in this systematic review. A phase III randomized controlled trial demonstrated that adding olanzapine to antiemetic prophylaxis reduces the likelihood of nausea among adult patients who are treated with high emetic risk antineoplastic agents. Randomized controlled trials also support an expanded role for neurokinin 1 receptor antagonists in patients who are treated with chemotherapy. Recommendation Key updates include the addition of olanzapine to antiemetic…

Citation impact

629
total citations
FWCI
75.30
Percentile
100%
References
110
Citations per year

Authors

17

Topics & keywords

Keywords
  • Medicine
  • Aprepitant
  • Antiemetic
  • Nausea
  • Vomiting
  • Carboplatin
  • Chemotherapy-induced nausea and vomiting
  • Guideline
UN Sustainable Development Goals
  • Good health and well-being
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