Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy
University of Wisconsin–Madison · University of California San Diego
Abstract
Abstract Hepatic steatosis is characterized by abnormal and excessive accumulation of lipids within hepatocytes. It is an important feature of diffuse liver disease, and the histological hallmark of nonalcoholic fatty liver disease (NAFLD). Other conditions associated with steatosis include alcoholic liver disease, viral hepatitis, human immunodeficiency virus (HIV) and genetic lipodystrophies, cystic fibrosis liver disease, and hepatotoxicity from various therapeutic agents. Liver biopsy, the current clinical gold standard for assessment of liver fat, is invasive and has sampling errors, and is not optimal for screening, monitoring, clinical decision‐making, or well suited for many types of research studies.…
Citation impact
- FWCI
- 21.83
- Percentile
- 100%
- References
- 93
Authors
4Topics & keywords
- Nonalcoholic fatty liver disease
- Fatty liver
- Magnetic resonance imaging
- Medicine
- Steatosis
- Liver biopsy
- Liver disease
- Radiology
- Good health and well-being