Alzheimer's Disease
Brown University · St. Elizabeth's Medical Center · +3 more institutions
Indexed incrossrefpubmed
Abstract
This review of Alzheimer's disease assembles a variety of findings relevant to the mechanism of the disease and ties them together using the current understanding of the basis of the loss of cognition: the accumulation of misfolded proteins, which cause oxidative and inflammatory damage to the brain and, ultimately, synaptic dysfunction.
Citation impact
4,439
total citations
- FWCI
- 125.89
- Percentile
- 100%
- References
- 191
Citations per year
Authors
2Topics & keywords
Topics
Keywords
- Medicine
- Disease
- Mechanism (biology)
- Neuroscience
- Alzheimer's disease
- Cognition
- Oxidative damage
- Oxidative stress
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